Description
Sermorelin and Ipamorelin is a research peptide blend that combines a GHRH analog with a ghrelin receptor agonist to examine growth hormone regulation. Sermorelin (GHRH 1–29) activates the GHRH receptor to increase cAMP/PKA signaling, while Ipamorelin stimulates GHS-R1a through Gq/11-coupled calcium flux. This blend is employed in preclinical models investigating endocrine peptide synergy, GH release kinetics, and hypothalamic–pituitary signaling mechanisms.
For research use only. Not for human consumption.
References:
Bowers CY et al., Endocrinology, 1990 126(2):1165–1171
Frohman LA et al., Front Neuroendocrinol, 2002 23(3):257–291
Kojima M et al., Nature, 1999 402(6762):656–660




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