Hexarelin (5mg x 10), CJC-1295 no DAC (5mg x 10)

Description

Hexarelin and CJC-1295 no DAC (Mod GRF 1-29) are synthetic research peptides used in experimental models to investigate growth hormone axis regulation and somatotropic signaling pathways. Hexarelin is a potent hexapeptide growth hormone secretagogue that binds the growth hormone secretagogue receptor (GHS-R1a), activating Gq/PLC and calcium-dependent intracellular signaling involved in GH release and peptide-mediated metabolic regulation. CJC-1295 no DAC is a stabilized analog of growth hormone–releasing hormone (GHRH 1-29) that selectively activates the GHRH receptor, stimulating adenylate cyclase and cAMP-dependent pathways in pituitary somatotrophs. Preclinical research utilizes the combined activation of GHS-R1a and GHRH receptors to study synergistic growth hormone secretion, hypothalamic–pituitary feedback loops, and endocrine receptor pharmacology.

For research use only. Not for human consumption.

References:
Camanni F et al., J Endocrinol Invest, 1998 21(9):646–654
Frohman LA et al., Endocr Rev, 2001 22(6):606–648
Ghigo E et al., Eur J Endocrinol, 2001 145(1):1–10