AICAR 50mg

Description

AICAR is a synthetic nucleoside analog structurally related to adenosine monophosphate (AMP). AICAR research primarily investigates its role as an activator of AMP-activated protein kinase (AMPK), a central regulator of cellular energy balance and metabolic signaling pathways. Upon cellular uptake, AICAR is converted to an AMP-mimetic metabolite that interacts with AMPK-associated pathways under controlled laboratory conditions.

In vitro and animal studies commonly examine how AMPK activation influences glucose transport, lipid metabolism, mitochondrial activity, and inflammatory signaling markers. Major research areas include skeletal muscle energy regulation, adipose tissue metabolic responses, immune cell signaling modulation, and cell proliferation dynamics. These biological systems are important in laboratory research because they provide measurable biochemical and transcriptional endpoints for studying energy-sensing mechanisms and metabolic pathway regulation without implying clinical or human application.

For research use only. Not for human consumption.

References:
Corton JM et al., Eur J Biochem, 1995 229(2):558–565
Hardie DG et al., Nat Rev Mol Cell Biol, 2012 13(4):251–262
Winder WW et al., Am J Physiol, 2000 279(5):E1106–E1112