Description
Kisspeptin-10 is a synthetic decapeptide (Tyr-Asn-Trp-Asn-Ser-Phe-Gly-Leu-Arg-Phe-NH₂) corresponding to the active fragment of the KISS1 gene product. It binds to the GPR54 (KISS1R) receptor, activating Gq-mediated signaling cascades and modulating gonadotropin-releasing hormone (GnRH) expression in preclinical studies. Kisspeptin-10 serves as a tool for exploring reproductive and neuroendocrine peptide signaling.
For research use only. Not for human consumption.
References:
Kotani M et al., J Biol Chem, 2001 276(37):34631–34636
Oakley AE et al., Endocr Rev, 2009 30(6):713–743
de Roux N et al., N Engl J Med, 2003 349(17):1614–1627
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